Dear Friends,

We have just received incredibly exciting news from a doctor whose research was funded by IFF, Dr. Mark Souweidane at Weill Cornell Medical College and Memorial Sloan-Kettering Cancer Center. Results from a groundbreaking study led by Dr. Souweidane and published in the esteemed Lancet Oncology promises a true beginning of a cure for DIPG – a type of extremely aggressive brain tumor that has taken too many beloved children.

Your donations helped seed the initial funding dollars that have led to the eventual implication and trial for CED. It is because of your continued support that we are able to get one step closer to our goal: finding a cure.

You can read more from Dr. Souweidane below. Thank you for the difference you are making in the lives of so many children and families impacted by pediatric brain tumors.

Cheryl and Phil Yagoda

From Dr. Souweidane:

After a career-long research initiative, I’m proud to announce that the findings from the CED clinical trial are of such pinnacle importance that the results have been published in the most esteemed oncology journal in the world (link to manuscript included below). This publication validates a hypothesis that I put forth more than 20 years ago, and it came to fruition because of the support I received from families and organizations like the Ian’s Friends Foundation.

Twenty-eight children were treated over the course of five years, and we have been able to provide irrefutable evidence that validates convection-enhanced delivery as an efficient method to deliver drugs directly into DIPG tumors with no systemic toxicity. Said simply, this work proves that we can now get drugs where they need to be and eliminate them from where they should not be when treating children for DIPG.

Please believe me when I tell you that I have held the children so close to my heart every step of the way, and I have gone gray (literally) over the painstaking process required to get here. Your support has been part of something very important, and this is only the beginning.


With tremendous gratitude,
Mark M. Souweidane, MD, FACS, FAAP
Vice Chair and Professor, Department of Neurological Surgery
Director of Pediatric Neurosurgery
Weill Cornell Medical College and Memorial Sloan-Kettering Cancer Center